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Thistubing is then connected to the stopcock andis filled approximately halfway withheparinized saline.
Toxicity is principally dueto metabolism of ethylene glycol, in the presence of calcium,to oxalic acid, which is toxic to the kidneys and may causeobstructive renal failure related to oxalate crystals.
It was soon realizedthat the active moiety was paraamino benzene sulfonamide,and the dye part was not essential.
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